EFSA: Sucralose is safe and does not cause cancer

By Will Chu

- Last updated on GMT

EFSA's examination of sucralose has found no safety issues after a scientific paper found a link between the sweetener & cancer. © iStock
EFSA's examination of sucralose has found no safety issues after a scientific paper found a link between the sweetener & cancer. © iStock

Related tags Food European food safety authority Sugar

Scientific evaluations of sucralose, conducted by The European Food Safety Authority (EFSA), find no link between the sweetener and cancer.

Published in the EFSA Journal​, the findings are a direct response to allegations made by Italian researcher Morando Soffritti of the Ramazzini Institute.

The Institute’s trials​ with mice were suggestive of sucralose’s harmful effects but its results were largely dismissed by the food industry​, critical of its study design and methodology.

EFSA concluded that "the available data did not support the conclusions of the authors,” ​agreeing that the researchers used an unconventional design resulting in inconclusive, unreliable data.

The Panel also noted the lack of a mode of action and failure to meet considerations for a cause–effect relationship between sucralose intake and tumour development.

Moreover, there was no reliable evidence of in vivo​ genotoxicity.

ISA response

The International Sweeteners Association’s (ISA) chairman Robert Peterson welcomed the findings commenting that “this scientific opinion from EFSA is entirely consistent with the global scientific and regulatory consensus that sucralose is safe.”

The association added that sucralose can be a useful tool, when used in place of sugar and as part of a balanced diet, in helping reduce overall sugar and calorie intake, as well as manage blood glucose levels.

“Low calorie sweeteners are also non-cariogenic, which means that they do not contribute to tooth decay.”

Scrutiny of sucralose stretches back to 1989, when EFSA (known as Scientific Committee on Food (SCF)) first conducted a safety assessment of the sweetener.

This was followed up in 2000, where an acceptable daily intake (ADI) of 15 milligrams per kilogram of body weight mg/kg was set.

Fast forward to the end of 2015, where EFSA decided to expand the sweetener’s use in foods for special medical purposes for children.

Sucralose, listed as E 955 in Europe, is around 600 times sweeter than sugar that is used in over 4,500 food, beverage and pharmaceutical products around the world.

In 2011, sucralose accounted for 27.9% of the global sweetener market worth €1.015 billion ($1.146 bn), according to Leatherhead Food Research.

Source: EFSA Journal

Published online ahead of print:  doi.org/10.2903/j.efsa.2017.4784

“Statement on the validity of the conclusions of a mouse carcinogenicity study on sucralose (E 955) performed by the Ramazzini Institute.”

Authors: Fernando Aguilar et al.

Related news

Show more

Related products

show more

Download Sweet Trends Report 2024 by Südzucker

Download Sweet Trends Report 2024 by Südzucker

Content provided by Südzucker AG | 01-Jul-2024 | White Paper

For the fourth time, Südzucker has conducted a research study on consumer needs and purchase drivers in processed food & drinks, which will be another...

Your partner in plant-based meat alternatives

Your partner in plant-based meat alternatives

Content provided by ADM to be Archived | 15-May-2024 | White Paper

Harness our technical expertise and world-class portfolio of high-quality ingredients and formulations to create elevated, chef-driven, plant-based meat...

Oat Beta-glucan – Clean Label Texturizer

Oat Beta-glucan – Clean Label Texturizer

Content provided by Lantmännen Biorefineries AB | 21-Nov-2023 | White Paper

In today's health-conscious world, consumers seek transparent labels and natural ingredients.

Related suppliers

Follow us


View more