Excellims and Washington State University expand agreement

Excellims Corporation has signed an exclusive worldwide license agreement with Washington State University for a new instrumental method to interface an Ambient Pressure Ion Mobility Spectrometer (APIMS) to a Mass Spectrometer (MS).

It is an expansion of an existing patent licensing agreement between the provider of high performance ion mobility spectrometers (HPIMS) and the university.

Developed in the lab of Dr Herbert H. Hill Jr., a reagents professor at Washington State University and researcher in the IMS field for 45 years, the technology will improve the ion transmission into the MS, potentially overcoming sensitivity challenges when interfacing APIMS to MS.

“This new approach will enable APIMS to interface to MS systems that were challenged with scan speed and sensitivity. With much greater ion transmission from this brilliant new approach, we can effectively complete ion mobility mass data acquisition for fast eluting HPLC peaks,” said Dr Ching Wu, president and CEO of Excellims Corporation.

Excellims introduced its MA3100 product line two years ago combining HPIMS technology with a dual gate APIMS-MS approach developed by Dr Brian Clowers in Dr Hill’s lab.

The new patent from the lab will boost performance of Excellims’ HPIMS-MS products and make the HPIMS-MS more amenable for complex samples with low-abundance compounds of interest.

Dr Hill said the agreement will allow researchers in a variety of academic research and industrial research fields to have a more powerful tool based on ion mobility spectrometry.

“With this advancement of the ion mobility technology, many analyses that could not be accomplished by state-of-the-art HPLC or MS can become reality, especially when a high resolution ion mobility device like the Excellims’ spectrometer is used.”

Excellims’ said the high resolution and linear response range of its instruments has brought IMS into the pharmaceutical and food industries for applications such as cleaning validation and quality control.