Intestinal damage and inflammation caused by ulcerative colitis could be eased by long chain polyunsaturated fatty acids (LC-PUFAs), Spanish researchers report recently.
Writing in the January Journal of Nutrition, researchers from the University of Granada, Spain, said they had given rats with experimental ulcerative colitis a diet of either monounsaturated or LC-PUFAs in the form of olive oil, fish oil or animal-based phospholipids.
The two-week study showed that rats fed with fish oil showed significantly less macroscopic and microscopic colonic damage compared to the olive oil and phospholipid groups. These results suggest that a balanced diet containing omega-3 LC-PUFAs could reduce the inflammation and mucosal damage of ulcerative colitis, the authors said.